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Research Associate I, Staging and Logistics, CGR

Frederick National Laboratory for Cancer Research

This is a Contract position in Foster City, CA posted December 30, 2022.

Research Associate I, Staging and Logistics, CGR Job ID: req3174 Employee Type: exempt full-time Division: Clinical Research Program Facility: Rockville: 9615 MedCtrDr Location: 9615 Medical Center Drive, Rockville, MD 20850 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc.

The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases.

Accountability, Compassion, Collaboration, Dedication, Integrity and Versatility; it’s the FNL way.

PROGRAM DESCRIPTION The Cancer Genomics Research Laboratory (CGR) investigates the contribution of germline and somatic genetic variation to cancer susceptibility and outcomes in support of the NCI’s Division of Cancer Epidemiology and Genetics (DCEG), the world’s most comprehensive cancer epidemiology research group.

CGR is located at the NCI-Shady Grove campus in Gaithersburg, MD and operated by Leidos Biomedical Research, Inc.

We care deeply about discovering the genetic and environmental determinants of cancer, and new approaches to cancer prevention, through our contributions to the molecular, genetic, and epidemiologic research of the 70 investigators in DCEG.

Working in concert with epidemiologists, biostatisticians and basic research scientists in DCEG’s intramural research program, CGR provides the capacity to conduct genome-wide discovery studies and targeted regional approaches to identify the heritable determinants of various forms of cancer.

This includes the design and analysis of high throughput studies using various types of “–omics” technologies such as array
– and sequence-based genome-wide association studies, studies of tumor characteristics using integrated genomic data analysis, and molecular epidemiologic studies based on novel assays focused on the metabolome and microbiome.

KEY ROLES/RESPONSIBILITIES The Cancer Genomics Research (CGR) laboratory is a fast-paced, high throughput organization that supports histology, molecular and digital pathology, nucleic acid extraction, sample staging, genotyping, sequencing, and analysis for genetic and epidemiologic studies for the investigators within DCEG.

CGR is recruiting a Research Associate I position within Extraction and Staging laboratory that supports sample extraction, quantitation and normalization of extracted nucleic acid for all sequencing and genotyping efforts.

The RAI position will work within our high throughput, highly automated DNA QC laboratory to support biospecimen, reagent and materials management activities.

The successful candidate will work seamlessly within the Staging team and will have responsibility for the day-to day execution of laboratory processes and applications including: Support for sample logistics, including preparation of sample collection kits for distribution to collaborators, receipt and organization of incoming sample shipments and reconciliation/organization for downstream activities Responsible for QC practices including nucleic acid quantitation and qualification, normalization, volume checking, and residual creation Responsible for plating DNA and RNA on automation platforms Use of LIMS for sample management Responsible for performing, documenting, and reporting results and deviations for a variety of procedures in the laboratory, governed by SOPs React to any non-conformances or opportunities for improvement, by taking appropriate corrective actions in consultation with management, development team and other relevant staff members As needed, use of automated liquid handling robotics and/or manual methods in BSL-2 controlled laboratory space to support biospecimen aliquoting tasks for both in house and outsourced assays Organization of samples, including sorting by tube type and relabeling as needed for automation workflows Support for sample inventory efforts, including freezer consolidation activities and preparation of samples for return to external collaborators and/or NCI Central Repository Perform routine maintenance of laboratory equipment and maintain a clean work area Practice safe work habits, including complying with all safety, health and environmental rules and regulations Other duties as assigned and available BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below: Possession of a bachelor’s degree from an accredited college or university according to the Council for Higher Education Accreditation in a field related to biomedical research.

(Additional qualifying experience may be substituted for the required education).

Foreign degrees must be evaluated for U.S.

equivalency.

A minimum of two (2) years of related molecular biology experience Ability to obtain and maintain a security clearance Experience with DNA and RNA assessment for quantity and quality utilizing various instruments Strong written and oral communication skills Computer literacy (Microsoft Office products, general computer proficiency) Ability to apply routine mathematics to laboratory calculations PREFERRED QUALIFICATIONS Candidates with these desired skills will be given preferential consideration: Experience with DNA and RNA extraction from a variety of biospecimen types Experience in utilization of a LIMS for sample and process tracking Familiarity with liquid handling robotics (use and maintenance, including but not limited to Tecan, Biomek, Dynamic Devices platforms) Experience with data analysis and visualization tools such as Excel, Spotfire, Tableau Demonstrated attention to detail Ability to prioritize and multi-task JOB HAZARDS This position is subject to working with or have potential for exposure to infectious material, requiring medical clearance and immunizations This position may require continuous or intermittent exposure to and exertion in environmental conditions such as working outdoors, temperature extremes, humidity extremes.

etc.

as part of the job.

Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW) readytowork